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Personalized Medicine for Parkinson's Disease New Concepts and Future of Individualized Managementкнига
- Авторы: Fedosova Anna, Titova Nataliya, Kokaeva Zarema, Shipilova Natalia, Katunina Elena, Klimov Eugene
- Год издания: 2023
- Издательство: MDPI
- Местоположение издательства: Basel, Switzerland
- Объём: 216 страниц
- ISBN: 978-3-0365-6211-7
- Академическое издание
- DOI: 10.3390/books978-3-0365-6211-7
- Аннотация: Personalized medicine for Parkinson’s disease is a growing and emerging concept in light of recent recognition that Parkinson’s is a syndromic condition affecting multiple neurotransmitter systems as well as brain and extracranial structures. The clinical expression is thus heterogeneous, and presentation age can range from the 30s to the 90s, with PD in older patients being associated with significant neuropathological comorbidity as well, involving not just misfolded alpha synuclein deposition but also amyloid and tau. Traditional and largely guideline-driven “one size fits all” management strategies adopted in clinical practice are therefore often inadequate in holistic management of a patient, particularly when aspects of motor and nonmotor symptoms are taken into consideration. In this book of JPM, we present several possible strands of personalized medicine in PD, ranging from genomic precision medicine to digital “checklists” to ensure delivery of holistic personalized medicine involving nonpharmacological strategies, as well.
- Добавил в систему: Кокаева Зарема Григорьевна