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Activation of maternal behavior of albino rats after combined treatment with dopamine and opioid receptor antagonists in low dosesстатья
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 25 декабря 2013 г.
- Авторы: Dobryakova Y.V., Belyaeva Y.A., Stovolosov I.S., Dubynin V.A., Kamenskii A.A.
- Журнал: Bulletin of Experimental Biology and Medicine
- Том: 142
- Номер: 2
- Год издания: 2006
- Издательство: Springer Nature
- Местоположение издательства: Switzerland
- Первая страница: 161
- Последняя страница: 164
- Аннотация: We studied the effect of D1/D2 antagonist haloperidol on maternal motivation in nursing albino rats. Haloperidol in a dose of 0.2 mg/kg significantly attenuated parental reactions and motor and exploratory activities. In a lower dose (0.1 mg/kg) the drug produced the same effect on maternal behavior (number of approaches to newborns) without reducing motor activity. The effect of low-dose haloperidol was different after naloxone treatment (0.2 mg/kg intranasally): the number of pup transfers increased significantly. The detected phenomenon indicates good prospects of combined treatment with agents modifying the cerebral dopaminergic and opioid systems as the method for correction of disorders in maternal behavior.
- Добавил в систему: Дубынин Вячеслав Альбертович